ESTROGEL® is used as part of hormone replacement therapy (HRT) to treat symptoms of estrogen deficiency, such as hot flushes, night sweats, and vaginal dryness, which may occur during menopause or after surgical removal of the ovaries.

In fertility treatments, ESTROGEL® is often prescribed to support the uterine lining during Assisted Reproductive Technology (ART) procedures, such as in vitro fertilisation (IVF).

Estradiol helps create a receptive environment for embryo implantation and early pregnancy development.

The typical dosage is one pump (0.75 mg of estradiol) applied to clean, dry skin once daily. Your doctor may adjust the dosage based on your individual needs, up to a maximum of four pumps per day.

The gel should be applied to areas such as the arms, shoulders, or inner thighs, avoiding the breasts and mucous membranes.

Allow the gel to dry completely before dressing.

If you forget to apply ESTROGEL®, use it as soon as you remember, unless it is close to the time of your next scheduled dose. In that case, skip the missed dose and continue with your regular schedule.

Do not apply extra gel to make up for the missed dose. Contact your doctor if you are unsure.

In case of overdose, such as applying excessive amounts of gel, wash the area with soap and water and contact your doctor or the Poisons Information Centre (Australia: 13 11 26) for advice.

Symptoms may include nausea, vomiting, or breast tenderness.

Store ESTROGEL® below 25°C in its original packaging to protect it from light and moisture. Do not freeze the gel.

Keep it out of reach of children and ensure the pump pack is securely closed after use.

Common side effects include skin irritation at the application site, headaches, nausea, breast tenderness, and bloating. Some women may experience mood changes or dizziness.

Rare but serious side effects include signs of blood clots, such as swelling or pain in the legs, chest pain, or difficulty breathing.

Contact your doctor immediately if you experience severe symptoms.

ESTROGEL® may interact with medications such as anticoagulants, thyroid medications, or certain herbal supplements.

Inform your doctor about all medications, vitamins, or herbal products you are taking to avoid potential interactions.

Excessive alcohol intake may influence the effectiveness of HRT, so it is best to limit alcohol consumption.

How does ESTROGEL® work in fertility treatments? ESTROGEL® delivers estradiol through the skin into the bloodstream, helping to maintain a thick and healthy uterine lining. This supports embryo implantation and early pregnancy during ART procedures.

Can I apply ESTROGEL® myself? Yes, ESTROGEL® is designed for self-application. Your doctor or nurse will provide instructions on how to apply the gel correctly. Ensure the skin is clean, dry, and free of lotions or oils before application.

What should I do if I experience side effects? Mild side effects, such as skin irritation or headaches, are common and usually temporary. If you experience severe symptoms, such as chest pain or difficulty breathing, contact your doctor immediately. Your healthcare team is here to support you.

Can ESTROGEL® be used during pregnancy? No, ESTROGEL® is not intended for use during pregnancy. If you suspect you may be pregnant while using ESTROGEL®, contact your doctor immediately for advice.

How should I store ESTROGEL®? Store ESTROGEL® below 25°C in its original packaging, away from light and moisture. Ensure the pump pack is securely closed after use.

Ace provides accurate and independent information medically reviewed on prescription medications. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.