Human Immunodeficiency Virus (HIV)
Human immunodeficiency virus (HIV) is an infection that attacks the body’s immune system.
Human Immunodeficiency Virus (HIV)
What Is Human Immunodeficiency Virus (HIV)?

Human immunodeficiency virus (HIV) is the virus that causes HIV infection. HIV affects the immune system by attacking and destroying CD4 cells. The CD4 cells are part of your immune system that help in fighting infections. Without CD4 cells, it is hard for your body to fight serious infections and certain cancers, making those infected more susceptible to getting sick.

If left untreated, HIV can destroy the immune system and can lead to Acquired Immunodeficiency Syndrome (AIDS), which is the most advanced stage of HIV infection.

 

 

How common is HIV?

Around 30,000 people are living with HIV in Australia. There were 757 new diagnoses in 2024 — a 27% decline since 2015, continuing a long-term downward trend driven by testing, treatment, and PrEP.

Male-to-male sex remains the most common route of transmission, accounting for 62% of new diagnoses in 2024, followed by heterosexual contact and, less commonly, injecting drug use.

Australia is among the countries closest to reaching the UNAIDS 95-95-95 targets: as of 2024, an estimated 92% of people living with HIV had been diagnosed, 97% of those were on antiretroviral therapy, and 98% of those on treatment had an undetectable viral load. This is the basis of U=U (Undetectable = Untransmittable) — a person with an undetectable viral load cannot transmit HIV through sex.

 

 

What Are The Symptoms Of Human Immunodeficiency Virus (HIV)?

At about 2-4 weeks after infection with HIV, the virus multiplies rapidly and some people develop flu-like symptoms, such as fever, headache, and rash. After this stage, the virus continues to multiply, but at very low levels. People may not have any symptoms at this point. It can take several years before signs of severe infection and opportunistic infections* develop.

Without treatment, HIV advances to AIDS in about 10 years (can be more or less in some people). At this point, the immune system is typically severely damaged. HIV transmission can occur at any stage after infection, even if the person has no symptoms.

*Opportunistic infections are infections that occur more frequently and are more severe in people with weakened immune systems, including people with HIV.

 

 

What Causes Human Immunodeficiency Virus (HIV)?
HIV is transmitted through contact with HIV-infected body fluids, including blood, semen, pre-seminal fluids, vaginal fluids, rectal fluids, and breast milk.

HIV is mainly spread by:

    • Anal or vaginal sex with an HIV infected person without using a condom or taking medications to prevent or treat HIV
    • Sharing injection drug equipment, such as needles, with an HIV infected person
    • Mother-to-child transmission can occur from a woman with HIV to her child during pregnancy, childbirth, or breastfeeding
HIV cannot be transmitted by:
    • Shaking hands or hugging a person who has HIV
    • Sharing objects such as dishes, toilet seats, or doorknobs used by a person with HIV
    • HIV is not spread through the air or in water or by mosquitoes, ticks, or other blood-sucking insects

 

How is Human Immunodeficiency Virus (HIV) Diagnosed?

The only way to know your HIV status is to get tested. In Australia, HIV testing is guided by individual risk rather than offered as a routine universal screen. Testing is available through GPs, sexual health clinics, community testing services, and self-collection (home) test kits.

Testing is recommended for anyone who may have been exposed to HIV. More frequent, regular testing is advised for people at higher ongoing risk — including sexually active gay and bisexual men, people whose partner is living with HIV, and people who inject drugs — with the recommended interval depending on level of risk.

If you are unsure whether or how often you should be tested, your GP or a sexual health clinic can help you assess your risk and advise you.

 

 

How is Human Immunodeficiency Virus (HIV) treated?

There is no cure for HIV, but effective treatment allows people living with HIV to stay healthy and live long lives. HIV medicines are called antiretrovirals, and treatment usually involves a combination of them — often combined into a single daily pill, making it far more manageable than in earlier years.

Taking medication consistently is essential. Skipping or stopping doses can allow the virus to develop resistance, which can stop the medicines working.

 

Preventing HIV: PrEP and PEP

Pre-Exposure Prophylaxis (PrEP) is medication taken by HIV-negative people to prevent infection. Oral PrEP (tenofovir/emtricitabine) is subsidised on the PBS for eligible individuals in Australia.

A long-acting injectable form (cabotegravir, brand name Apretude) has been approved by the TGA but is not yet PBS-subsidised — as of 2025 it is available only through a limited compassionate access program for people who cannot take daily oral PrEP.

Speak with your GP or a sexual health clinic about whether PrEP is right for you.

Post-Exposure Prophylaxis (PEP) is an emergency course of medication taken to prevent infection after a potential HIV exposure. It must be started as soon as possible, and within 72 hours, and is available through hospital emergency departments and sexual health clinics.

 

 

Medications

The following specialty medications may be available at Ace, a specialty pharmacy for HIV.

Brand

Drug

Class

Biktarvy

emtricitabine + tenofovir alafenamide + bictegravir

NRTI + INSTI combination

Descovy

emtricitabine + tenofovir alafenamide

NRTI combination

Dovato

lamivudine + dolutegravir

NRTI + INSTI combination

Evotaz

atazanavir + cobicistat

PI + pharmacokinetic enhancer

Genvoya

emtricitabine + tenofovir alafenamide + elvitegravir + cobicistat

NRTI + INSTI + pharmacokinetic enhancer

Juluca

rilpivirine + dolutegravir

NNRTI + INSTI combination

Kaletra

lopinavir + ritonavir

PI combination

Odefsey

emtricitabine + tenofovir alafenamide + rilpivirine

NRTI + NNRTI combination

Prezcobix

darunavir + cobicistat

PI + pharmacokinetic enhancer

Symtuza

emtricitabine + tenofovir alafenamide + darunavir + cobicistat

NRTI + PI + pharmacokinetic enhancer

Triumeq

abacavir + lamivudine + dolutegravir

NRTI + INSTI combination

NRTI = nucleoside reverse transcriptase inhibitor; NNRTI = non-nucleoside reverse transcriptase inhibitor; PI = protease inhibitor; INSTI = integrase strand transfer inhibitor

Please contact Ace Pharmacy if you have questions or concerns about these medications.

 

 

How Can Ace Help You?

With Ace, you’ll benefit from:

    • Expert Support — Our dedicated team of health concierges is always available to answer your questions, provide guidance, and help you navigate your condition with confidence.
    • Specialty Medication — We offer a wide range of specialty medications and support services, designed specifically for those living with chronic illnesses. Whether you’re looking for help managing a specific condition, or simply need access to the medications you need, we’ve got you covered.
    • A Wide Range of Conditions — From diabetes to heart disease, and everything in between, we help manage a variety of special condition

 

Take control of your health and well-being, and start your journey to better health with Ace today.

 

 

Disclaimer
Ace provides accurate and independent information medically reviewed prescription medications. This material is provided for educational purposes and is not intended for medical advice, diagnosis or treatment.
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